Description
Quick-Reference Overview Matrix
For efficient laboratory evaluation, the matrix below consolidates the core analytical, storage, and cross-reference parameters of Selank 10mg.
| Core Parameter | Technical Summary & Quick Data | Internal Cross-Reference |
|---|---|---|
| Purity & Grade | ≥ 98% HPLC Certified Sterile filtered, vacuum-desiccated lyophilized solid engineered for contaminant-free receptor tracking. | View High-Purity Series → |
| Primary Target Path | GABAergic & Monoaminergic Regulation: Modulates neurotransmitter turnover paths and extends enkephalin lifespans without benzodiazepine-like sedation side effects. | Nootropic Research Series → |
| Storage Protocol | Lyophilized: -20°C to -80°C (Up to 24 months). Reconstituted: 2°C to 8°C (Must use within 10–14 days). | Buy Reconstitution Diluents → |
| Synergistic Assays | Frequently evaluated alongside regulatory nootropics like Semax to profile parallel memory and stress adaptive pathways in identical animal models. | Explore Semax/Selank Blend → |
What Is Selank?
What Is Selank?
Selank is a synthetic regulatory heptapeptide analog of the naturally occurring immunomodulatory peptide Tuftsin. It features an added Pro-Gly-Pro (PGP) tripeptide chain at its C-terminus, structural packaging engineered specifically to resist swift proteolytic degradation by blood and tissue endopeptidases. Selank operates inside central nervous system models primarily by influencing neurotransmitter dynamics, making it a key compound for studying non-sedative emotional stability and neuro-immune signaling networks.
Selank 10mg Overview
Our Selank 10mg formulation provides high-yield analytical purity designed strictly for in vitro biochemical screenings and in vivo neurological evaluation maps. Every vial undergoes rigorous freeze-drying protocols under vacuum to prevent ambient heat or atmospheric moisture from fracturing the linear amino acid bonds.
| Parameter | Specification |
|---|---|
| Product Format | 10mg Vial (Lyophilized Powder) |
| Sequence | Thr-Lys-Pro-Arg-Pro-Gly-Pro |
| Molecular Formula | C33H57N11O9 |
| Molecular Weight | 751.9 g/mol |
| Purity Level | ≥ 98% (HPLC Monitored) |
| Physical Appearance | Sterile filtered, white lyophilized cake |
| Core Research Focus | Enkephalinase Inhibition, GABAergic Allosteric Modulation, Neurotransmitter Kinetics (Serotonin/Dopamine) |
Regulatory Compliance Notice: This product is synthesized, distributed, and intended solely for laboratory research and development purposes. It is strictly not for human therapeutic use, clinical trials, or agricultural applications. Analytical evaluation sheets (HPLC/MS results) are systematically logged per batch.
Research Applications of Selank Peptide
Research Applications of Selank Peptide
In cognitive and behavioral neuroscience publications, Selank is widely evaluated across physiological adaptation and regulatory stress models. Researchers utilize this compound to analyze:
- Enkephalin Preservation Dynamics: Studying how the peptide limits the structural breakdown of endogenous enkephalins inside plasma and brain tissues, analyzing its downstream connection to alternative pain or emotional paths.
- Neurotransmitter Turnover Rates: Tracking rapid shifts in the concentration and breakdown rate of serotonin (5-HT) and dopamine within regional cerebral structures.
- mRNA Inflammatory Modulations: Evaluating shifts in interleukin expressions (IL-6 alternatives) inside nerve cell cultures subjected to acute environmental stress.
Selank Mechanism of Action
Selank targets complex neurochemical balance paths without interacting with traditional central benzodiazepine receptor anchors:
- Acts as a weak allosteric modulator of **GABA-A receptors**, optimizing natural GABAergic inhibitory transmissions without generating baseline motor-sedation or muscle relaxation artifacts.
- Inhibits the regulatory enzymes (enkephalinases) responsible for the chemical cleavage of enkephalins, augmenting the baseline lifespan of these natural opioid ligands.
- Upregulates **Brain-Derived Neurotrophic Factor (BDNF)** transcriptions inside hippocampal arrays, reinforcing structural nerve protection and synaptic plasticity metrics.
Research Overview: Benefits vs. Technical Risks
| Observed Research Benefits | Technical Risks & Limitations |
|---|---|
| • Non-Sedative Stabilization: Provides clear anxiolytic research metrics without triggering the coordination faults or physical dependencies associated with classic GABA agonists. | • Subtle Assay Biomarkers: Lacking heavy sedative readouts, recording behavioral parameter changes in baseline animal assays demands sensitive, high-resolution tracking gear. |
| • PGP Peptidase Defense: The C-terminal Pro-Gly-Pro tripeptide delivers deep protective advantages against cell-culture exopeptidase degradation paths. | • Fluid Reconstitution Lifespan: Following diluent mixing, the linear bond chain can still face thermal denaturing if stored outside laboratory cold-storage constraints. |
Peptide Comparison Matrix
Peptide Comparison Matrix
To optimize experimental setups, the comparison matrix below differentiates Selank 10mg from other single-sequence nootropic and regulatory research peptides in our catalog:
| Peptide Compound | Primary Mechanism | Core Research Focus | Target Receptors | Molecular Weight |
|---|---|---|---|---|
| Selank 10mg(This Product) | Tuftsin Analogue (GABA) | Enkephalinase block, emotional stability assays, neurotransmitter balance. | GABA-A / Enkephalin | 751.9 g/mol |
| Semax 10mg | ACTH Analogue (MC4) | BDNF/NGF upregulation, memory consolidation, neurovascular modeling. | MC4 Receptor | 813.9 g/mol |
| Epitalon 10mg | Telomerase Inducer | Cellular lifespan tracking, telomere maintenance, pineal modeling. | Epigenetic DNA | 390.4 g/mol |
Storage & Handling Instructions
Storage & Handling Instructions
To avoid structural degradation of the linear peptide and keep your batch yield protected against premature hydrolysis, apply the following climate metrics:
- LONG-TERM Lyophilized State: Keep frozen inside laboratory configurations operating at -20°C or -80°C. Stable for up to 24 months.
- SHORT-TERM Transit Stability: The freeze-dried state stays highly resilient up to 25°C for 3 weeks max while in shipment transport routes. Freeze upon delivery.
- POST-RECONSTITUTION Liquid Solubilization: Store inside laboratory refrigeration between 2°C and 8°C. Exhaust the testing compound fluid completely within 10–14 days. Do not agitate or refreeze.
Reconstitution Guidelines
- Allow the Selank vial to naturally reach room temperature equilibrium before opening.
- Cleanse the top rubber entry septa interface with a fresh isopropyl sterile wipe.
- Slowly slide 1ml or 2ml of sterile bacteriostatic water down the inside glass barrier to limit mechanical stress factors.
- Do not shake. Gently swirl the vial horizontally in concentric circles until the white cake powder fully dissolves into a clear liquid layer.
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