Description
Quick-Reference Overview Matrix
For efficient laboratory evaluation, the table below provides a consolidated overview of the structural and functional criteria of Melanotan II 10mg.
| Core Parameter | Technical Summary & Quick Data | Internal Cross-Reference |
|---|---|---|
| Purity & Grade | ≥ 98% HPLC Certified Sterile filtered, cyclic structure engineered for high-affinity receptor tracking without sequence artifacts. | View High-Purity Series → |
| Primary Target Path | Melanocortin Agonism: Melanocortin Agonism:</strong> Targets MC1R receptors to study photoprotective melanogenesis, skin matrix pigmentation, and cellular defense against UV-induced aging, while interacting with MC3R/MC4R pathways for central metabolic profiling. | Explore Anti-Aging Series → |
| Storage Protocol | Lyophilized: -20°C to -80°C (Up to 24 months). Reconstituted: 2°C to 8°C (Must use within 14 days maximum). | Buy Reconstitution Diluents → |
| Synergistic Assays | Frequently cross-referenced with non-pigmenting alternative behavioral lines like PT-141 to map selective receptor binding configurations. | Pair with Melanotan 1 10mg → |
What Is Melanotan II?
What Is Melanotan II?
Melanotan II (MT-2) is a synthetic, cyclic heptapeptide analog of the alpha-melanocyte stimulating hormone (α-MSH). Structurally configured with an internal lactam ring, this modification delivers exceptional enzymatic resistance and a significantly extended biological half-life compared to its linear native counter-sequences. MT-2 acts as a potent, non-selective agonist at central and peripheral melanocortin receptors, making it a critical asset in research environments studying the regulation of melanin synthesis, systemic energy expenditure, and autonomic sexual behavior responses.
Melanotan II 10mg Overview
Our Melanotan II 10mg formulation features an ultra-pure, crystal-desiccated lyophilized powder engineered strictly for institutional laboratories and microfluidic receptor screening. Freeze-dried under deep vacuum bounds, the integrity of the cyclic chain is secured against moisture integration and ambient degradation paths during storage.
| Technical Feature | Specification Level |
|---|---|
| Molecular Mass | 1024.2 g/mol |
| Sequence Blueprint | Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2 |
| Chemical Formula | C50H69N15O9 |
| Purity Baseline | ≥ 98.0% via HPLC Integration |
| Core Target Nodes | MC1R Melanogenesis, MC3R Systemic Regulation, MC4R Central Erectile Responses & Appetite Signals |
Research Dynamics of Melanotan II
Research Dynamics of Melanotan II
In analytical biochemistry, lipid metabolism, and behavioral dermatology publications, Melanotan II is evaluated broadly across overlapping central and peripheral pathways. Researchers utilize this compound to analyze:
- Melanogenesis Stimulation: Mapping how the compound stimulates melanin production inside melanocyte cultures without requiring high exposure to ultraviolet radiation loops.
- Appetite and Satiety Cascades: Investigating the down-regulation of nutritional drive models via central MC4 receptor pathways.
- Central Erectile Adaptations: Tracking autonomic erectile simulation loops that originate directly within hypothalamic neural pathways rather than local vascular smooth-muscle cells.
Melanotan II Mechanism of Action
Melanotan II exerts its biological effects by acting as a non-selective biomimetic ligand that binds with high affinity to multiple melanocortin receptor isoforms:
- MC1R Agonism: Binds to melanocytes, upregulating adenylate cyclase activity and cAMP paths, driving the synthesis of eumelanin (dark pigment).
- MC4R Agonism: Stimulates central pathways in the hypothalamus, altering satiety signals to depress baseline feeding drive behaviors while concurrently driving autonomic erectile signals down the spinal column.
Analytical Summary: Benefits vs. System Limitations
| Observed Research Values | Technical Assay Constraints |
|---|---|
| • Multi-Pathway Profiling: Permits parallel tracking of pigmentation, metabolic appetite control, and behavioral drives using a single compound matrix. | • Off-Target Melanocytic Noise: Non-selective agonism means that studying appetite pathways can introduce overlapping pigment adjustments, potentially complicating clean data splits. |
| • Lactam Ring Resiliency: The cyclic loop structure offers excellent stability against rapid degradation by serum endopeptidases in active tissue models. | • Pressor In Vivo Variances: Prolonged, high-concentration exposure in animal assays can lead to acute variations in mean arterial blood pressure tracking. |
Peptide Comparison Matrix
Peptide Comparison Matrix
To support advanced experimental setups, the matrix below outlines the operational and structural differences between Melanotan II 10mg and related central receptor compounds in our catalog:
| Research Compound | Operational Engine | Core Analytical Focus | Target Nodes | Molecular Base |
|---|---|---|---|---|
| Melanotan II 10mg(This Product) | Non-Selective Agonist | Melanogenesis tracking, skin pigmentation, appetite suppression profiles. | MC1 / MC3 / MC4 | 1024.2 g/mol Cyclic |
| PT-141 10mg | Selective CNS Agonist | Hypothalamic dopamine mapping, non-vascular erectile response, libido models. | MC3 / MC4 | 1025.2 g/mol Cyclic |
Laboratory Climate & Handling Standards
Laboratory Climate & Handling Standards
To safely shield the cyclic lactam link layout from structural deformation and avoid early baseline hydrolysis vectors, adhere to strict storage boundaries:
- DEEP FREEZE Lyophilized Solid: Lock inside laboratory freezers running at -20°C or -80°C. Secures structural sequence baseline metrics for up to 24 months.
- TRANSIT WINDOW Vacuum Desiccation: The dry vacuum cake resists ambient delivery transport up to 25°C for 3 weeks max. Transfer to sub-zero environments instantly post-delivery.
- LIQUID PHASE Solubilized State: Store inside laboratory refrigeration between 2°C and 8°C. Exhaust the testing fluid completely within 14 days maximum. Never freeze fluid mixtures.
Reconstitution Protocol
- Allow the 10mg Melanotan II vial to naturally adjust to room temperature equilibrium before removing its security seal.
- Sanitize the top rubber entry septum thoroughly using a high-grade isopropyl alcohol wipe.
- Slowly slide 1ml or 2ml of sterile bacteriostatic water down the interior glass envelope to minimize structural kinetic shock paths.
- Do not shake or vortex. Gently swirl the vial horizontally in circular patterns until the white solid powder fully dissolves into a perfectly transparent liquid layer.
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